Will the Purest Sleep Diffuser work with any essential oil? January 23, 2019 18:06 Yes, any essential oil scent can be used in the device. Related articles Are the USB cables for the Rohm and/or Hushh units compatible with the adaptive fast charging power adapters? Can you control the intensity of the scent in the Purest Diffuser? How large of an area does the Purest Sleep Diffuser cover? What is the break-in period for Marpac Unplug?