Unzip and take off the top half of the Zip-N-Wash cover (the white part), and put it in the washing machine with a mild detergent. You can then use a damp washcloth or sponge with warm water and mild soap for the spot on the foam. Dab the area with the water and mild soap, pressing down to make sure you get the area well. Be sure to continuously rinse your rag to make sure the fluid isn't just being pushed around. Do not soak the mattress. When you're done, prop the mattress up and air dry. You can do this outside or you can use a fan to help circulate the air in the room. For future reference though, look into getting a mattress protector to place on top of the Zip-N-Wash cover so that spills or "accidents" won't penetrate through the cover.